Cuproptosis-related lncrnas

Author: rafg

August undefined, 2024

WebOct 14, 2024 · Objective . Cuproptosis is a newly discovered copper-independent cell death modality, and limited evidence suggests the critical implications in human cancers. … WebAug 17, 2024 · A cuproptosis-related lncRNAs signature for prognosis, chemotherapy, and immune checkpoint blockade therapy of low-grade glioma A cuproptosis-related …

Prognostic signature construction and immunotherapy response …

WebIn this study, cuproptosis-related lncRNAs was screened by Pearson correlation analysis. Then, univariate, Least Absolute Shrinkage and Selection Operator (LASSO), and multivariate Cox regression were conducted to identify 6 cuproptosis-related lncRNAs (AC090541.1, AC009226.1, NIFK-AS1, AC027097.2, AC026355.2, and AC106028.2) … WebNov 6, 2024 · As per the results from the TCGA database, the prognostic value of 13 cuproptosis-related lncRNAs is validated, among which 8 cuproptosis-related lncRNAs can be employed to construct the cuproptosis-related lncRNA model to predict the OS of KIRC patients. Moreover, KIRC patients are divided into the high-risk group and the low … list of endangered animals of pakistan

Prognostic signature construction and immunotherapy …

WebFeb 17, 2024 · Ten cuproptosis-related lncRNAs were identified and a novel risk model was constructed. A signature based on ten cuproptosis-related lncRNAs was an independent prognostic predictor for COAD. Mutational burden analysis suggested that patients with high-risk scores had higher mutation frequency and shorter survival. … WebMar 15, 2024 · Results: A cuproptosis-related long noncoding RNAs (lncRNAs) signature was constructed. Using quantitative polymerase chain reaction (qPCR) trial, we verified that the expressions of GLIS2-AS1, LINC01230, and LINC00592 in LUAD cell lines and tissues were consistent with the above screening results. WebOct 7, 2024 · However, few prognostic models of cuproptosis-related Lncrnas have been reported in LUAD. In this study, a novel 3-lncrNA prognostic model was identified based on cuproptosis-related genes. Compared with the traditional prediction model, it only contains 2 Lncrnas, so it is relatively easy to use. First, we divided TCGA-LUAD into a test set … imagination and creativity ppt

A Prognostic Cuproptosis-Related LncRNA Signature for Colon ...

Exploration of the role of Cuproptosis genes and their related …

WebApr 11, 2024 · And the mechanism of cuproptosis-related lncRNAs in endometrial cancer progression is still not clear. Therefore, further research on this topic is needed. This … WebApr 10, 2024 · Background: Glioma patients often experience unfavorable outcomes and elevated mortality rates. Our study established a prognostic signature utilizing cuproptosis-associated long non-coding RNAs (CRLs) and identified novel prognostic biomarkers and therapeutic targets for glioma.Methods: The expression profiles and related data of … list of endangered animal speciesWebNov 15, 2024 · Identification of cuproptosis-related long non-coding ribonucleic acid signature as a novel prognosis model for colon cancer Identification of cuproptosis-related long non-coding ribonucleic acid signature as a novel prognosis model for colon cancer Authors Rong Xu 1 2 , Xin Wu 3 , Ashuai Du 4 , Qiangqiang Zhao 5 , He Huang 1 2 … list of endangered cats

"WebJan 7, 2024 · Determination of CLPS in LUAD. After 441 cuproptosis-related lncRNAs were selected, 10 cuproptosis-related lncRNAs were obtained through the univariate Cox ratio risk analysis, which were significantly associated with the survival in LUAD patients (Fig. 2A). Based on these 10 lncRNAs, LASSO Cox regression was conducted to screen … " - Cuproptosis-related lncrnas

Cuproptosis-related lncrnas

WebJul 15, 2024 · The aim of our study was to construct a prognostic profile based on cuproptosis-associated lncRNAs to predict the prognosis of ccRCC and to study the … WebSep 24, 2024 · This study aimed to explore the relationship between cuproptosis-related lncRNA and hepatocellular carcinoma (HCC) with regard to immunity and prognosis. …

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WebApr 13, 2024 · FIGURE 1.Identification of the cuproptosis-related lncRNAs (CRLs). (A) Co-expression of lncRNA and cuproptosis-related genes.(B) The forest map shows the …

WebApr 10, 2024 · PDF Background: Glioma patients often experience unfavorable outcomes and elevated mortality rates. Our study established a prognostic signature... … WebApr 13, 2024 · FIGURE 1.Identification of the cuproptosis-related lncRNAs (CRLs). (A) Co-expression of lncRNA and cuproptosis-related genes.(B) The forest map shows the lncRNA of different risk groups; red represents high-risk lncRNAs and green represents low-risk lncRNAs.(C) A general cross-validation curve of the paired likelihood deviance.(D) …

WebFeb 24, 2024 · The correlation between cuproptosis and long non-coding RNAs (lncRNAs) has been increasingly studied recently. In this study, a novel cuproptosis-related lncRNA prognostic signature was developed to investigate biochemical recurrence (BCR) and tumor immune landscape in prostate cancer (PCa). WebJan 3, 2024 · Four cuproptosis-related lncRNAs were used to construct a prognostic lncRNA signature, which was an independent factor in predicting OS in HCC patients. Kaplan–Meier curves showed significant differences …

WebMar 3, 2024 · lncRNA is an important regulator of gene expression, which widely affects the progression of cancer, cardiovascular disease, and diabetes.27lncRNAs can participate in tumor growth and metastasis process through transcriptional and post-transcriptional mechanisms28and are able to affect the expression of carcinogenic transcription …

WebSep 1, 2024 · Cuproptosis-related lncRNAs can have clinical diagnostic and therapeutic implications for LUAD. In the present study, we used bioinformatics analysis to obtain … imagination and creativity govWebNov 1, 2024 · Whether cuproptosis-related genes have prognostic predictive value has not been clarified. In this study, uni-/multi-variate Cox and Lasso regression analyses were applied to construct a risk model based on cuproptosis … imagination and community marilynne robinsonWebJul 22, 2024 · Background: Cuproptosis is a new type of cell death that induces protein toxic stress and eventually leads to cell death. Hence, regulating cuproptosis in tumor cells is a new therapeutic approach. However, studies on cuproptosis-related long noncoding RNA (lncRNA) in head and neck squamous cell carcinoma (HNSC) have not been found. imagination agency londonWebApr 1, 2024 · The correlation between cuproptosis-related lncRNAs and immune microenvironment was elucidated, where 7 immune cells and 8 immune-correlated … imagination and creativity differenceWebApr 1, 2024 · The correlation between cuproptosis-related lncRNAs and immune microenvironment was elucidated, where 7 immune cells and 8 immune-correlated pathways were found to be differentially expressed ... imagination and creativityWebCuproptosis-related lncRNAs linked to survival were identified using co-expression and univariate Cox regression. Furthermore, consensus cluster analysis divided the lncRNAs into two subtypes. Subsequently, we established a signature model consisting of seven cuproptosis-related lncRNAs (AC073534.2, AC021321.1, HYI-AS1, PPP1R26-AS1, … list of endangered plants in indiaWebSep 1, 2024 · Identification of the cuproptosis-related lncRNAs. a LASSO regression screened of cuproptosis-related lncRNAs at the minimum point of cross-validation.b … list of endangered animals 2020