Nettet17. des. 2008 · Lineage-specific transcription factors and the evolution of gene regulatory networks. Nature is replete with examples of diverse cell types, tissues and … Nettet24. apr. 2014 · This observation is in line with a recent report showing that FOXP3 in Tregs is recruited to Treg- and Tconv-shared preexisting DNase-accessible sites to exert its lineage-specifying functions. 26 In addition to candidate regulators derived from motif analyses, we also predicted subset-specific TF networks solely on the basis of DGE data.
Identification of Lineage-Specific Transcription Factors That …
Nettet26. sep. 2024 · Thus, lineage-specific expression of two major factors, ThPOK and Runx3, which drive the CD4/CD8 lineage dichotomy, requires Bcl11b, or more specifically, … Nettet6. mar. 2024 · ILCs are classified into different groups depending on their developmental and effector program defined by the expression of lineage-specifying transcription … town of natick gis
ZFP462 targets heterochromatin to transposon-derived ... - bioRxiv
Nettet1. jan. 2014 · Our current challenges include defining the conserved mechanisms that are utilized by these lineage-specifying transcription factors to coordinate gene expression programs in different settings as well as the mechanistic events that contribute to the differential downstream consequences that these factors mediate in unique cellular … Nettet26. sep. 2024 · One such lineage-specifying transcription factor, Zbtb7b, also known as T-helper-inducing POZ/Krueppel − like factor (ThPOK), is a member of the BTB-POZ … Nettet1. a. : descent in a line from a common progenitor. b. : derivation. the gun's direct lineage is in the 1960s Erik Larson. 2. : a group of individuals tracing descent from a common … town of natick gis map