Anti-synthetase syndrome is an autoimmune disease associated with interstitial lung disease, arthritis, and myositis. As a syndrome, this condition is poorly defined. Diagnostic criteria require one or more antisynthetase antibodies (which target tRNA synthetase enzymes), and one or more of the following three … See more It is postulated that autoantibodies are formed against aminoacyl-tRNA synthetases. The synthetases may be involved in recruiting antigen-presenting and inflammatory cells to the site of muscle or lung … See more Prognosis is largely determined by the extent of pulmonary damage. See more In the presence of suspicious symptoms a number of test are helpful in the diagnosis: • Anti-tRNA antibody testing • Electromyography See more Unfortunately, treatment for the anti-synthetase syndrome is limited, and usually involves immunosuppressive drugs such as glucocorticoids. For patients with pulmonary … See more

Antisynthetase-Syndrom - DocCheck Flexikon

WebNational Center for Biotechnology Information WebAnti-synthetase syndrome is an autoimmune disease characterized by interstitial lung disease (ILD), non-erosive arthritis, myositis, Raynaud’s phenomenon, unexplained fever and/or mechanic’s hands. Reference Values. Describes reference intervals and additional information for interpretation of test results. normal weight gain for 6 month old

【专题笔谈】自身抗体在肌炎相关间质性肺疾病中的应用价值

WebAntisynthetase syndrome (ASyS) is an autoimmune disease clinically manifested most often by interstitial lung disease, myositis, and arthritis. Raynaud's syndrome, fever, and rashes … WebApr 12, 2024 · Aminoacyl-tRNA synthetases form the protein family that controls the interpretation of the genetic code, with tRNA aminoacylation being the key chemical step during which an amino acid is assigned to a corresponding sequence of nucleic acids. WebFeb 12, 2024 · Background Anti-synthetase syndrome (ASSD) is a chronic autoimmune condition characterized by antibodies directed against an aminoacycl transfer RNA synthetase (ARS) along with a group of clinical features including the classical clinical triad: inflammatory myopathy, arthritis, and interstitial lung disease (ILD). ASSD is highly … how to remove square taper cranks